Endocrine Abstracts

Objective: The rate of surgical cure of acromegaly with transphenoidal hypophysectomy varies greatly. Factors that have been previously noted to affect outcome include tumour size and level of growth hormone (GH). We evaluated clinical factors associated with surgical outcome in our patient series.Method: Retrospective study of clinical data and surgical outcome of patients who underwent transphenoidal hypophysectomy for acromegaly by a single surgeon at...

Objective: Transphenoidal hypophysectomy is currently the primary treatment for patients with acromegaly. Advances in medical and radiotherapy treatment options have resulted in uncertainty whether surgery should remain the treatment of choice for all acromegalics. The surgical cure rate for acromegaly is variable and there is a need to accurately counsel patients regarding the likelihood of successful surgical cure. We examined how lateral tumour extension into the cavernous ...